Why the study?
Patients undergoing emergency surgery for intra-abdominal infection often receive treatment antibiotics and may not benefit from additional pre-incisional antibiotics.
Does pre-incisional antibiotics reduce the occurrence of surgical site infections in patients undergoing emergency appendectomy?
Does pre-incisional antibiotics reduce the occurrence of surgical site infections in patients undergoing emergency appendectomy?
May not reduce SSIs with pre-incisional antibiotics in emergency appendectomy; leaves open need for RCTs before practice change.
Background: Antibiotics within an hour of incision reduce the incidence of surgical site infection (SSI) in clean-contaminated abdominal surgery. However, patients undergoing emergency surgery for an intra-abdominal infectious process often receive treatment antibiotics and may not benefit from additional pre-incisional antibiotics (POA). We hypothesized that POA would not lead to a reduction in the occurrence of SSIs following emergency appendectomy.
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Hendrix et al. (2025) studied this question.
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