December 7, 2005European Heart Journal
QRS duration and late mortality in unselected post-infarction patients of the revascularization era
Why the study?
Does prolonged QRS duration predict total mortality in survivors of acute MI in the revascularization era?
Population
1455 survivors of acute myocardial infarction in sinus rhythm and under 76 years of age, 98% received…
Comparison
Prolonged QRS duration (>=120 ms) vs Normal QRS duration (<120 ms)
Design
Cohort
Follow-up
22+/-5 months
Authors
Discussion
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Member takes
Implication
Supports QRS prolongation for post-MI mortality risk stratification; leaves open whether it extends LVEF-guided decisions in the revascularization era.
Structured PICO
Does prolonged QRS duration predict total mortality in survivors of acute MI in the revascularization era?
P
Population
1455 survivors of acute myocardial infarction (MI) in sinus rhythm and under 76 years of age, 98% received reperfusion/revascularization therapy (90% PCI).
I
Intervention
Prolonged QRS duration (>=120 ms)
C
Comparator
Normal QRS duration (<120 ms)
O
Outcome
Total mortalityhard clinical
Prolonged QRS duration remains a strong independent predictor of late mortality in post-MI patients treated in the revascularization era, particularly in those with LVEF <=30%.
Cite This Study
Bauer et al. (2005) studied this question.