Key result
Soccer players with mild or moderate mitral valve prolapse had no positive late potentials or T-wave alternans, showing no significant electrophysiological differences versus athletes without MVP.
Why the study?
Do non-invasive cardiac electrophysiological indices and cardiorespiratory adaptations differ in young athletes with mild or moderate mitral valve prolapse compared to healthy athletes and sedentary individuals?
Cross-Sectional (n=60)
Do non-invasive cardiac electrophysiological indices and cardiorespiratory adaptations differ in young athletes with mild or moderate mitral valve prolapse compared to healthy athletes and sedentary individuals?
Mild-to-moderate mitral valve prolapse in young athletes does not appear to adversely affect non-invasive electrophysiological risk markers for sudden cardiac death or cardiorespiratory performance.
Answers are grounded in this paper and cite their sources.
Supports reassuring electrophysiological profile for mild-moderate MVP in young athletes; leaves open prospective validation for SCD risk stratification.
BACKGROUND: Cardiac disorders constitute the most common causes of sudden cardiac death (SCD) and mitral valve prolapse (MVP) is one of the cardiac structural causes in young populations. The aim of this study was to evaluate some reliable non-invasive electrophysiological variables of SCD in young athletes with mild or moderate MVP and to compare them with their cardiorespiratory adaptations. DESIGN: The study population comprised of 40 amateur male soccer players, who were equally subdivided into those with (group A, aged 20.4+/-4.5 years) and without (group B, 18.4+/-2.4 years) MVP and 20 healthy age-matched sedentary individuals (group C). METHODS: All subjects underwent echo study for left ventricular mass index (LVMI) estimation, treadmill spiro-ergometric test for maximal oxygen uptake (VO2max) measurement and continuous ambulatory 24-h ECG recordings for arrhythmias detection and heart rate variability (HRV) analysis. Furthermore, groups A and B were also submitted to signal-averaged electrocardiogram for late potentials (LP) assessment and to submaximal exercise test for T-wave alternans (TWA) detection. RESULTS: Maximal oxygen uptake, LVMI and HRV index were enhanced in all athletes compared to group C (P<0.05). Resting QTc interval was significantly prolonged only in group B (by 3.7%) compared to C (P<0.05), whereas no significant difference was found between A and B. No positive LP or TWA were observed in all subjects. Significant correlation was found only between HRV index and VO2max in all groups. CONCLUSIONS: Athletes with mild or moderate MVP do not present any significant difference in non-invasive cardiac electrophysiological indices as well as in cardiorespiratory performance, compared to healthy ones. It seems that long-term exercise induced adaptations overlap any cardiac autonomic disorders in cases of mild-to-moderate MVP severity.
No takes yet. Share an insight, caveat, or question.
Κουτλιάνος et al. (2004) conducted a cross-sectional in Mitral valve prolapse (n=60). Mild or moderate mitral valve prolapse (exposure) vs. Athletes without mitral valve prolapse and healthy sedentary individuals was evaluated on Non-invasive cardiac electrophysiological indices (late potentials, T-wave alternans, HRV, QTc) and cardiorespiratory performance. Soccer players with mild or moderate mitral valve prolapse had no positive late potentials or T-wave alternans, showing no significant electrophysiological differences versus athletes without MVP.
Synapse has enriched 10 related papers. Consider them for comparative context: