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Platelet labeling with Cr 51 : ACD better than EDTA Human platelets were known to survive for between 8 and 11 days, but in 1964 the mechanism of platelet death was a subject of controversy. Was platelet death random or a result of cellular senescence? Researchers were hindered in efforts to solve this mystery by the available methodology. Platelet labeling with the radioisotope Cr 51 using EDTA induced platelet sequestration and the death of two-thirds of the platelet population.
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Insel et al. (2004) studied this question.
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