Key result
In healthy Indian adults assessed by 4D XStrain speckle tracking echocardiography, left ventricular strain and rotational parameters, including global longitudinal strain and peak twist, were significantly greater in men than in women (p<0.01).
Why the study?
Normal value ranges of LV strain and rotational parameters had not been comprehensively established in healthy Indian adults using 4D speckle tracking echocardiography.
Cross-Sectional (n=80)
No
This study establishes normal reference ranges for LV strain and rotational mechanics using 4D speckle tracking echocardiography in healthy Indian adults, highlighting significant sex and age-related differences.
Sex-specific LV strain references may be warranted in Indian adults; leaves open validation and clinical utility.
XStrain 4D Speckle tracking echocardiography is a novel approach to address both the strain deformation and rotational mechanics of LV. The aim was to comprehensively present the normal value ranges of LV strain and rotational parameters of healthy Indian adults after assessment with this innovative technique. The study population comprising of 80 adults (58 males, 22 females; Group A < 30 years, Group B > 31 years) is revealing the values of Global longitudinal strain (GLS), Global longitudinal strain rate (GLSR), Transverse strain (TS), Transverse strain rate (TSR), Shear and Shear rate are greater in men than in women (p<0.01) and moreover in Group A, Global Circumferential strain (GCS), Global Circumferential strain rate (GCSR), Global Radial strain and Global Radial strain rate (GRSR) were similarly higher in men. Peak apical rotation, peak twist, twist rate and untwist rate values were again greater in men (p<0.01) and increased with advancing age. This is the first study to present a candid and comprehensive analysis of extensive parameters of LV strain and rotational mechanics in healthy Indian adults.
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Akhil Mehrotra (2022) conducted a cross-sectional in Healthy adults (n=80). 4Dimensional XStrain Speckle Tracking Echocardiography was evaluated on Normal value ranges of LV strain and rotational parameters (p=<0.01). In healthy Indian adults assessed by 4D XStrain speckle tracking echocardiography, left ventricular strain and rotational parameters, including global longitudinal strain and peak twist, were significantly greater in men than in women (p<0.01).
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