Key result
In patients with acute heart failure and type 2 diabetes, intra-hospital mortality was 6.3% and was significantly associated with longer diabetes duration, history of heart disease, and lower LVEF.
Why the study?
The concomitant presence of acute heart failure and diabetes is a major cause of morbidity and mortality, prompting the need to determine characteristics and predictors of intra-hospital mortality.
Cross-Sectional (n=63)
No
In patients with acute heart failure and type 2 diabetes, intra-hospital mortality is significantly associated with longer diabetes duration, history of heart disease, lack of prior heart failure therapy, hypoxia, severe dyspnea, and reduced LVEF.
Identifies mortality predictors in acute HF with T2D; hypothesis-generating and should not yet change practice.
Background The concomitant presence of acute heart failure (AHF) and diabetes is a major cause of morbidity and mortality. Our study aims to determine the characteristics of AHF in patients with type 2 diabetes and the predictors of intra-hospital mortality. Methods This was a descriptive and analytical retrospective study, carried out in the Internal Medicine and Cardiovascular Diseases departments of the Soavinandrina Hospital Center over a period of 2 years. The diagnosis of AHF and diabetes was made according to the criteria of the European Society of Cardiology and the American Diabetes Association, respectively. Results The prevalence of AHF in type 2 diabetes was 16.9%. With a male predominance, the mean age of the patients was 61.6 ± 10.2 years. The average of diabetes duration was 5.5 ± 4.5 years, and which was unbalanced in 82.5%. AHF was mainly manifested by breathlessness (88.9%), bilateral pulmonary crepitations (79.4%) and ankle swelling (71.4%). Left ventricular ejection fraction (LVEF) was reduced in 69.8% of cases. AHF was mostly decompensated by infections (49.2%). With a rate of 6.3%, intra-hospital mortality was significantly correlated with the average of diabetes duration (p = 0.0002), history of heart disease (p = 0.0032), absence previous basic treatment for heart failure (Angiotensin-converting enzyme inhibitors, beta-blockers, diuretics, p < 0.05), arterial oxygen desaturation in ambient air ≤ 90% (p = 0.0106), severity breathlessness (p = 0.0398) and decrease in LVEF (p = 0.0140). Conclusion AHF in patients with type 2 diabetes is frequent and serious, requiring early, adequate, and multidisciplinary management. Therapeutic education and infection prevention are essential.
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Raharinavalona et al. (2022) conducted a cross-sectional in Acute heart failure and type 2 diabetes (n=63). In patients with acute heart failure and type 2 diabetes, intra-hospital mortality was 6.3% and was significantly associated with longer diabetes duration, history of heart disease, and lower LVEF.
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