The systolic white coat effect (office minus home blood pressure) was reversely associated with HbA1c (P=0.012), and masked hypertension was more prevalent in dysglycemia vs normoglycemia (P=0.036).
Cohort (n=5,025)
Is there a discrepancy between office blood pressure and home blood pressure monitoring in relation to glycemic status in middle-aged individuals?
In middle-aged individuals, worsened glycemic status is associated with a higher prevalence of masked hypertension and a lower systolic white coat effect, highlighting the importance of out-of-office BP monitoring in this population.
p-value: p=0.012
BACKGROUND: Masked hypertension is more common in individuals with type 2 diabetes than in individuals with normoglycemia. We aimed to explore if there is a discrepancy between office blood pressure (office BP) and home blood pressure monitoring (HBPM) in relation to HbA1c as well as glycemic status in 5,029 middle-aged individuals. METHODS: HBPM was measured in a subsample of 5,029 participants in The Swedish CardioPulmonary BioImage Study (SCAPIS), a population-based cohort of 50-64 years old participants. Both office BP and HBPM were obtained after 5 minutes' rest using the semiautomatic Omron M10-IT oscillometric device. White coat effect was calculated by subtracting systolic HBPM from systolic office BP. Participants were classified according to glycemic status: Normoglycemia, prediabetes, or diabetes based on fasting glucose, HbA1c value, and self-reported diabetes diagnosis. RESULTS: Of the included 5,025 participants, 947 (18.8%) had sustained hypertension, 907 (18.0%) reported taking antihypertensive treatment, and 370 (7.4%) had diabetes mellitus. Both systolic office BP and HBPM increased according to worsened glycemic status (P for trend 0.002 and 0.002, respectively). Masked hypertension was more prevalent in participants with dysglycemia compared with normoglycemia (P = 0.036). The systolic white coat effect was reversely associated with HbA1c (P = 0.012). CONCLUSIONS: The systolic white coat effect was reversely associated with HbA1c, and the prevalence of masked hypertension increased with dysglycemia.
Geijerstam et al. (Fri,) conducted a cohort in Dysglycemia (n=5,025). Home blood pressure monitoring vs. Office blood pressure was evaluated on Discrepancy between office BP and HBPM (white coat effect) in relation to HbA1c (p=0.012). The systolic white coat effect (office minus home blood pressure) was reversely associated with HbA1c (P=0.012), and masked hypertension was more prevalent in dysglycemia vs normoglycemia (P=0.036).
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