Key result
Senegalese NonSTEMI patients have significant coronary lesions in ~64% of cases, most often tri-truncular.
Why the study?
NonSTEMI is most often linked to non-occlusive coronary lesions yet mortality remains high, prompting evaluation of diagnostic and evolutionary aspects in patients presenting with NonSTEMI.
Cross-Sectional (n=52)
No
In a Senegalese cohort, NonSTEMI frequently presented with severe, multi-vessel coronary artery disease in high-risk patients, though optimal management was limited by financial barriers to coronary angiography and PCI.
NonSTEMI in Senegal often features tri-vessel disease with low in-hospital mortality; leaves open questions on PCI access and regional outcomes.
Introduction: Non-ST-elevation myocardial infarction (NonSTEMI) is most often associated with a non-occlusive coronary lesion. However, mortality remains high. The aim of this study was to evaluate the diagnostic and evolutionary aspects of patients presenting with NonSTEMI. Patients and methods: This was a descriptive cross-sectional study conducted from January 01, 2021 to June 31, 2021 in the cardiology department of Aristide Le Dantec Hospital It included all patients hospitalized for NonSTEMI in the study period. The data studied were clinical, paraclinical, therapeutic and evolutionary. Results: A total of 52 patients were included. Mean age was 60.69 years, with extremes of 32 and 86 years. The most common risk factors were hypertension (58.85%), diabetes (34.62%) and smoking (30.7%). Chest pain was the main symptom (73.1%). On physical examination, signs of heart failure were noted in 19.2% of cases. Troponinemia was positive in 94.2% of patients. Repolarization disorders occurred most frequently in the lateral territory (55.4%). ST-segment depression was most common (75%). Doppler echocardiography revealed segmental kinetic disorders in 22 patients (42.3%). Coronary angiography was performed in 36 patients. Significant lesions were found in 63.8% of cases, most often tri-truncular (56.5%). Fourteen patients underwent angioplasty. In-hospital mortality was 3.8%. Conclusion: NonSTEMI is a frequent clinical form of acute coronary syndrome, occurring most often in high-risk patients. It is the expression of coronary lesions that are often severe.
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Antoine et al. (2023) conducted a cross-sectional in Non-ST-elevation myocardial infarction (NonSTEMI) (n=52). Among 52 patients hospitalized for NonSTEMI in Senegal, significant coronary lesions were present in 63.8% of cases, most often tri-truncular, and in-hospital mortality was 3.8%.
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