Key result
The GRACE risk score demonstrated high discriminatory capacity for predicting hospital mortality in Chinese AMI patients aged ≥80 years (C statistic 0.767; CI 0.712-0.822).
Why the study?
Does the GRACE risk score accurately predict hospital mortality in Chinese AMI patients aged 80 and over?
Observational (n=386)
Does the GRACE risk score accurately predict hospital mortality in Chinese AMI patients aged 80 and over?
Effect estimate: C statistic 0.767 (95% CI 0.712-0.822)
The GRACE risk score is a valid and useful tool for predicting in-hospital mortality among Chinese AMI patients aged 80 and older.
May support risk stratification in elderly Chinese AMI patients; extends GRACE validation but leaves practice change open.
AIM: To detect the validity of the Global Registry of Acute Coronary Events (GRACE) risk score in predicting acute myocardial infarction (AMI) mortality of Chinese inpatients aged 80 and over. METHOD: Hospital mortality was defined as all-cause death rate of patients during hospitalisation. Using GRACE risk score to predict death risk, both discrimination (C statistic) and calibration (the predicted vs observed mortality based on the population with predicted risks) were evaluated. RESULTS: Three hundred eighty-six patients presenting with ST segment elevation AMI (STEMI) and non-STEMI were enrolled. The GRACE risk score ranged between 151 and 297, and the mortality was 23.3%. The overall discriminatory capacity of the GRACE model was high (C statistic 0.767, CI: 0.712-0.822). There was a high correlation (R(2) = 0.833) between the predicted and observed hospitalised AMI mortality. CONCLUSION: The GRACE score is a useful risk prediction model for hospital mortality of Chinese AMI patients aged 80 and over.
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Luo et al. (2013) conducted an observational in Acute myocardial infarction (n=386). GRACE risk score was evaluated on Hospital mortality (C statistic 0.767, 95% CI 0.712-0.822). The GRACE risk score demonstrated high discriminatory capacity for predicting hospital mortality in Chinese AMI patients aged ≥80 years (C statistic 0.767; CI 0.712-0.822).
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