Cardiovascular consequences of poor compliance to antihypertensive therapy
Why the study?
Do Angiotensin II receptor blockers (ARBs) improve medication adherence and cardiovascular outcomes compared to ACE inhibitors in patients requiring antihypertensive therapy?
Population
Patients requiring antihypertensive therapy, particularly those at risk of low adherence
Comparison
Angiotensin II receptor blockers (ARBs) vs Angiotensin-converting enzyme inhibitors or…
Design
Review
Authors
Discussion
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Member takes
Implication
Supports ARB preference for adherence in hypertension; leaves open outcome superiority versus ACE inhibitors.
Structured PICO
Do Angiotensin II receptor blockers (ARBs) improve medication adherence and cardiovascular outcomes compared to ACE inhibitors in patients requiring antihypertensive therapy?
P
Population
Patients requiring antihypertensive therapy, particularly those at risk of low adherence
I
Intervention
Angiotensin II receptor blockers (ARBs)
C
Comparator
Angiotensin-converting enzyme (ACE) inhibitors or other classes of antihypertensive agents
O
Outcome
Medication adherence and cardiovascular protection
ARBs should be considered as an alternative to ACE inhibitors in patients at risk of low adherence due to their better long-term tolerability.
Cite This Study
Grassı et al. (2011) studied this question.