Key Points
- Analyze the long-term decline in coronary heart disease mortality across Western nations to assess the relative impacts of reduced disease incidence versus improved treatment and prognosis.
- Evaluated 25-year epidemiological trends in coronary heart disease mortality, incidence rates, and clinical presentation patterns across Western countries.
- Assessed the comparative contributions of acute myocardial infarction therapies, chronic disease risk factor management, and primary prevention.
- Coronary heart disease mortality declined faster than incidence rates, shifting the main driver of mortality reduction from falling incidence in the 1970s and 1980s to improved prognosis and chronic risk factor management in later years.
- Hospitalizations for non-infarction coronary heart disease increased while definite myocardial infarctions declined, leading to an increased overall prevalence and total disease burden in an aging population.
Structured PICO
PPopulationPopulations in most western countries
Despite declining CHD mortality rates, the total burden of CHD has decreased less than expected due to an aging population and increased prevalence, highlighting the need for primary prevention.