Left bundle branch area pacing using stylet-driven pacing leads demonstrated a 90% procedural implant success rate with no instances of septal perforation.
Observational (n=20)
No
Left bundle branch area pacing using stylet-driven leads is a feasible and safe physiological pacing strategy with a 90% acute success rate in a low-to-medium volume center.
p-value: p=<0.001
Background The use of left bundle branch area pacing (LBBAP) as a substitute for conduction system pacing (CSP) is becoming increasingly popular. Thus, this study was performed to evaluate the feasibility, safety, and outcomes of LBBAP with stylet-driven pacing leads (SDL) in a tertiary care center in Eastern India. Materials and methods This single-center, retrospective study was conducted at the Department of Cardiology, Indira Gandhi Institute of Medical Sciences (IGIMS), Patna, Bihar, India. The study included data from 20 patients over one year, i.e., from December 2023 to December 2024. The procedure-related characteristics included fluoroscopy exposure duration, doses, and patterns of electrocardiograms (ECG) and intracardiac electrograms (EGM) that were documented during implantation. The Institutional Ethics Committee (IEC), IGIMS, Patna, Bihar, India, has granted ethical approval (approval no. 291/IEC/IGIMS/2025, dated January 9, 2025). Results Implant success was observed in 18 (90%) patients. Significant differences were observed in bundle branch block and pacing indications with p-values <0.001 and 0.002, respectively. It was noted that a highly statistically significant result was obtained when unipolar impedance and bipolar impedance were compared, with a p-value of 0.002. Conclusion Our study found that permanent LBBAP is a viable physiological pacing method with a 90% success rate. Moreover, septal perforation complications were not noted. Among the limitations of the study were the small number of patients, which might affect the efficiency of the results, and the shorter duration of time. Additionally, the study was retrospective; thus, similar records of some parameters were difficult to find.
Kumar et al. (Mon,) conducted a observational in Pacing indications (Atrioventricular Block, Sinus Node Dysfunction, Cardiac Resynchronization Therapy) (n=20). Left bundle branch area pacing (LBBAP) with stylet-driven pacing leads (SDL) was evaluated on Procedural Implant Success (p=<0.001). Left bundle branch area pacing using stylet-driven pacing leads demonstrated a 90% procedural implant success rate with no instances of septal perforation.