Key result
Cardiac resynchronization therapy using atriobiventricular pacing has emerged as a highly effective and widely used treatment for patients with heart failure and cardiac dyssynchrony.
This review summarizes the epidemiology, effects, patient selection, and practical aspects of cardiac resynchronization therapy in heart failure.
That cardiac dyssynchrony can contribute to a decline in cardiac efficiency has been recognized in one form or another for at least 50 years. Although revascularization and beta-blockers can improve cardiac synchrony, there was little interest in or awareness of this clinical entity until the advent of specific, highly effective therapy using atriobiventricular pacing, often described as cardiac resynchronization therapy. Over the last few years, significant advances in cardiac resynchronization therapy technology and the publication of large-scale clinical trials using cardiac resynchronization therapy devices in patients with heart failure have led to the widespread use of these devices. This review will briefly describe the complex nature of cardiac dyssynchrony, what is known about its epidemiology, the effects of cardiac resynchronization therapy, appropriate patient selection, practical aspects, such as implantation and monitoring, and some still unanswered questions.
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Viswanathan et al. (2006) conducted a review in Heart failure. Cardiac resynchronization therapy was evaluated. Cardiac resynchronization therapy using atriobiventricular pacing has emerged as a highly effective and widely used treatment for patients with heart failure and cardiac dyssynchrony.
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