May 18, 2011Circulation Cardiovascular Interventions
Intravascular Ultrasound Findings of Early Stent Thrombosis After Primary Percutaneous Intervention in Acute Myocardial Infarction
Why the study?
Do adverse IVUS findings (small lumen area, residual stenosis, edge dissection, tissue protrusion) predict early stent thrombosis in patients with acute myocardial infarction undergoing primary PCI?
Population
401 patients with acute myocardial infarction undergoing primary percutaneous intervention with baseline…
Comparison
Adverse IVUS features vs Absence of adverse IVUS features
Design
Cohort
Follow-up
≤30 days
Authors
Discussion
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Member takes
Implication
Adverse IVUS features were associated with early stent thrombosis after primary PCI; hypothesis-generating and requires randomized confirmation before guiding practice.
Structured PICO
Do adverse IVUS findings (small lumen area, residual stenosis, edge dissection, tissue protrusion) predict early stent thrombosis in patients with acute myocardial infarction undergoing primary PCI?
P
Population
401 patients with acute myocardial infarction undergoing primary percutaneous intervention with baseline intravascular ultrasound (IVUS) in the HORIZONS-AMI study (n=12 with early stent thrombosis, n=389 without).
I
Intervention
Adverse IVUS features (minimum lumen area <5 mm², significant residual stenosis, significant stent edge dissection, or significant tissue protrusion)
C
Comparator
Absence of adverse IVUS features
O
Outcome
Definite/probable early stent thrombosis ≤30 days after enrollmenthard clinical
Smaller final lumen area and inflow/outflow disease (residual stenosis or dissection) on IVUS are strongly associated with early stent thrombosis after primary PCI for acute myocardial infarction.
Cite This Study
Choi et al. (2011) studied this question.