What question did this study set out to answer?

To measure and characterize T1 and T2 relaxation times of human brain tissue using 4-Tesla magnetic resonance imaging.

June 1, 1996Radiology

MR relaxation times in human brain: measurement at 4 T.

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Authors

PJPeter JezzardUniversity of Oxford SDStefan DuewellLeiden University RBRobert S. BalabanNational Institutes of Health

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Implication

Quantitative MRI study reveals altered T1 and T2 relaxation times in the human brain at 4 T, indicating that relaxation shifts may offset high-field signal gains.

Key Points

To measure and characterize T1 and T2 relaxation times of human brain tissue using 4-Tesla magnetic resonance imaging.
T1 relaxation times were measured using progressive saturation, Look-Locker, and inversion-recovery interleaved echo-planar imaging sequences.
T2 relaxation times were quantified across brain tissues using standard spin-echo and spin-echo interleaved echo-planar imaging sequences.
T1 values were 1,724 ± 51 msec for gray matter, 1,043 ± 27 msec for white matter, 4,550 ± 800 msec for cerebrospinal fluid, 1,458 ± 38 msec for the caudate nucleus, and 1,372 ± 60 msec for the putamen.
T2 values reached 63 ± 6.2 msec in gray matter and 49.8 ± 2.2 msec in white matter.
Measured 4-T T1 values exceeded predictions extrapolated from lower-field strengths, whereas T2 values exhibited a slight decrease.

Cite This Study

Jezzard et al. (1996) studied this question.

synapsesocial.com/papers/6a1af70b7ff99bba064665ae https://doi.org/10.1148/radiology.199.3.8638004

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Implication

Quantitative MRI study reveals altered T1 and T2 relaxation times in the human brain at 4 T, indicating that relaxation shifts may offset high-field signal gains.

MR relaxation times in human brain: measurement at 4 T.

Discussion

Member takes

Implication

Key Points

Cite This Study

MR relaxation times in human brain: measurement at 4 T.

Discussion

Member takes

Implication

Key Points

Cite This Study

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