Complexities of Rett Syndrome and MeCP2: Figure 1.

### Introduction 1Rett syndrome (RTT, MIM 312750), originally described by the Austrian pediatrician Andreas Rett, is an X-linked neurodevelopmental disorder that primarily affects girls at a frequency of 1:10,000 live female births ([Rett, 1966][1]; [Hagberg, 1985][2]; [Laurvick et al., 2006][3