Key result
High LGE-CMR myocardial viability is linked to improved CABG recovery and ~5% in-hospital mortality.
Why the study?
While CABG improves outcomes in ischemic LV dysfunction, accurate patient selection remains critical, and assessing myocardial viability via LGE-CMR is a key predictor of surgical outcomes.
Does myocardial viability assessed by LGE-CMR predict postoperative outcomes in patients with impaired left ventricular function undergoing CABG?
Observational (n=37)
No
Does myocardial viability assessed by LGE-CMR predict postoperative outcomes in patients with impaired left ventricular function undergoing CABG?
Preoperative assessment of myocardial viability using LGE-CMR correlates with improved surgical recovery and can guide patient selection for CABG in ischemic LV dysfunction.
Answers are grounded in this paper and cite their sources.
LGE-CMR viability assessment may inform prognosis after CABG in ischemic LV dysfunction; leaves open whether it improves patient selection.
Background Coronary artery bypass grafting (CABG) improves outcomes in patients with ischemic left ventricular (LV) dysfunction, but accurate patient selection remains critical. Late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) imaging aids in assessing myocardial viability, a key predictor of surgical outcomes. This study aimed to evaluate the impact of myocardial viability on postoperative outcomes in patients undergoing CABG. Methods This was a single-center prospective analysis of clinical outcomes in 37 patients with impaired LV function (mean ejection fraction: 35.59%); myocardial viability was assessed using LGE-CMR prior to CABG. Patient demographics, perioperative details, and short-term outcomes, including in-hospital mortality and recovery metrics, were analyzed. Results Patients exhibited high myocardial viability (mean: 88.16%), with an average of 2.35 non-viable segments. In-hospital mortality was 5.4% (n=2), and the mean hospital stay was six days. Patients with greater viability demonstrated better recovery and fewer complications. Multivessel coronary artery disease was prevalent (94.6%, n=35), with tailored graft configurations addressing individual anatomical and disease complexities. Conclusion LGE-CMR is a valuable tool for predicting outcomes in ischemic LV dysfunction. Myocardial viability strongly correlates with improved surgical recovery, highlighting the importance of integrating LGE-CMR into preoperative decision-making. Further studies are required to explore the long-term impact of myocardial viability on treatment outcomes and quality of life.
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Aasim et al. (2024) conducted an observational in Ischemic left ventricular dysfunction (n=37). Coronary artery bypass grafting (CABG) was evaluated on In-hospital mortality and surgical recovery based on myocardial viability. In patients with ischemic left ventricular dysfunction undergoing coronary artery bypass grafting, high myocardial viability assessed by LGE-CMR was associated with improved surgical recovery and an in-hospital mortality rate of 5.4%.
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