Key result
Coronary artery bypass grafting significantly improved mean left ventricular ejection fraction from 29.76% preoperatively to 33.53% postoperatively in patients with baseline LVEF < 50%.
Why the study?
CABG is associated with better outcomes in ischemic heart disease patients with low ejection fraction, but its effect on LV systolic function and predictors of poor postoperative outcomes needed demonstration.
Does coronary artery bypass grafting improve left ventricular systolic function in patients with ischemic heart disease and LVEF < 50%?
Cross-Sectional (n=110)
No
Does coronary artery bypass grafting improve left ventricular systolic function in patients with ischemic heart disease and LVEF < 50%?
Answers are grounded in this paper and cite their sources.
CABG significantly improves early postoperative left ventricular ejection fraction in patients with ischemic heart disease and baseline LVEF < 50%, though diabetes, advanced diastolic dysfunction, and IABP use predict higher in-hospital mortality.
BACKGROUND: Coronary artery bypass grafting is known to be associated with better outcome in ischemic heart disease patients with low ejection fraction. We aim to demonstrate the effect of coronary artery bypass grafting (CABG) on left ventricle (LV) systolic function and to identify the predictors that adversely lead to postoperative poor outcome. RESULT: This is a cross-sectional prospective study; we included 110 patients with left ventricular ejection fraction (LVEF) < 50% who underwent CABG with a mean age of 56.1 ± 12.2 years old. Those patients were classified into two groups: group I, 76 (69%) patients with LVEF > 35%, and group II, 34 (31%) patients with LVEF < 35%. Our results as regards demographic and clinical data revealed that group II patients had a significantly higher prevalence of diabetes mellitus (DM) and Euro SCORE II compared to group I patients (p = 0.05 and < 0.001 respectively); otherwise, all other clinical predictors did not differ between the two studied groups. There was a significant improvement in LVEF post-surgery (p = 0.05) in both groups with observed no significant difference recorded for in-hospital mortality rate among patients with different groups. DM, significant diastolic dysfunction, and insertion of IABP are predictors of in-hospital mortality of the patients (p = 0.001, 0.03 and < 0.001, respectively) CONCLUSION: We concluded that there is a significant improvement of LV systolic function after CABG and hence better survival rate. DM, significant diastolic dysfunction, and perioperative insertion of IABP are predictors of mortality after cardiac surgery. Special care should be provided to such patients to improve their outcome.
No takes yet. Share an insight, caveat, or question.
Khaled et al. (2019) conducted a cross-sectional in Ischemic heart disease with left ventricular systolic dysfunction (n=110). Coronary artery bypass grafting (CABG) vs. Preoperative baseline was evaluated on Left ventricular ejection fraction (LVEF) (p=0.05). Coronary artery bypass grafting significantly improved mean left ventricular ejection fraction from 29.76% preoperatively to 33.53% postoperatively in patients with baseline LVEF < 50%.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: