Key result
Coronary artery bypass grafting did not significantly change overall mean left ventricular ejection fraction, but significantly improved it in patients with pre-operative LV dysfunction (from 40.05% to 45.85%).
Why the study?
The study was designed to evaluate changes in LV systolic function after CABG in patients with normal versus abnormal preoperative systolic function.
Does coronary artery bypass grafting improve left ventricular systolic function in patients with normal and abnormal pre-operative systolic function?
Comparison
Preoperative normal vs abnormal LV systolic function
Design
Prospective study
Follow-up
4 to 6 months
Authors
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CABG was associated with LVEF improvement in preoperative dysfunction but decline when normal; leaves open whether baseline LVEF guides patient selection.
Observational (n=47)
No
Does coronary artery bypass grafting improve left ventricular systolic function in patients with normal and abnormal pre-operative systolic function?
Absolute Event Rate: 53.66% vs 54.21%
p-value: p=0.677
Coronary artery bypass grafting improves left ventricular ejection fraction in patients with pre-operative LV dysfunction, but may lead to a decline in those with preserved baseline function.
Papestiev et al. (2019) conducted an observational in Coronary artery disease (n=47). Coronary artery bypass grafting vs. Pre-operative baseline was evaluated on Mean Left Ventricular Ejection Fraction (LVEF) (p=0.677). Coronary artery bypass grafting did not significantly change overall mean left ventricular ejection fraction, but significantly improved it in patients with pre-operative LV dysfunction (from 40.05% to 45.85%).
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