Key result
Post-CABG improvements in LVEF and GLS are linked to reduced mortality.
Why the study?
Markers of improvement in LV systolic function after CABG and their association with all-cause mortality were not well characterized.
Does improvement in LVEF and GLS after CABG predict reduced all-cause mortality in patients undergoing isolated CABG?
Cohort
No
Does improvement in LVEF and GLS after CABG predict reduced all-cause mortality in patients undergoing isolated CABG?
p-value: p=< .001
Improvements in LVEF and GLS following CABG are common, especially in those with lower baseline function, and are associated with reduced all-cause mortality.
Objective: To examine markers of improvement in left ventricular (LV) systolic function after coronary artery bypass grafting (CABG), assessed by changes (Δ) in LV ejection fraction (LVEF) and global longitudinal strain (GLS), and to evaluate the association between ΔLVEF/ΔGLS and all-cause mortality. Methods: Patients who underwent isolated CABG from 2006 to 2011 at Gentofte Hospital with a preoperative echocardiography within 30 days before and postoperative echocardiography 30 to 365 days after surgery were included. Multivariable linear regression identified clinical and echocardiographic predictors of ΔLVEF and ΔGLS. Cox proportional hazards regression models related these changes to all-cause mortality. Results: values < .001). Conclusions: Postoperative improvements in LVEF and GLS were common, occurred most often in patients with lower pre-CABG LV function, and were independently associated with reduced mortality.
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Ramadan et al. (2026) conducted a cohort in Coronary artery disease requiring CABG. Postoperative improvements in LVEF and GLS was evaluated on All-cause mortality (p=< .001). Postoperative improvements in LVEF and GLS after CABG were independently associated with reduced mortality (P<.001).
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