Key result
Bedtime administration of hypertension medications exerts greater therapeutic effect on asleep blood pressure and normalizes the 24-hour dipping pattern compared to morning dosing.
Why the study?
Does bedtime administration of hypertension medications improve ambulatory blood pressure regulation compared to morning administration in patients with hypertension?
Does bedtime administration of hypertension medications improve ambulatory blood pressure regulation compared to morning administration in patients with hypertension?
Answers are grounded in this paper and cite their sources.
Chronotherapy with bedtime dosing of conventional hypertension medications is a cost-effective strategy to enhance 24-hour blood pressure control and normalize dipping patterns.
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Hermida et al. (2012) conducted a review in Hypertension. Bedtime dosing of hypertension medications (chronotherapy) vs. Morning dosing was evaluated on Ambulatory blood pressure regulation (asleep BP and 24-h dipping pattern). Bedtime administration of hypertension medications exerts greater therapeutic effect on asleep blood pressure and normalizes the 24-hour dipping pattern compared to morning dosing.
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