Key result
Paediatric patients with long QT syndrome reported similar physical activity levels as healthy controls despite guideline recommendations restricting physical activity and use of beta-blockers.
Why the study?
Patients with LQTS often face physical activity restrictions and use beta-blockers, leaving it unclear whether their physical activity levels are lower than those of healthy controls.
Are physical activity levels lower in paediatric patients with long QT syndrome compared with healthy controls?
Case-Control
Are physical activity levels lower in paediatric patients with long QT syndrome compared with healthy controls?
p-value: p=< 0.0001
Paediatric patients with long QT syndrome maintain similar physical activity levels to healthy controls, challenging the real-world impact of guideline restrictions.
Activity levels in paediatric long QT syndrome match controls despite restrictions; leaves open real-world adherence and guideline effectiveness.
Background: Physical activity (PA) is important for cardiovascular health as well as social and emotional well-being of children. Patients with long QT syndrome (LQTS) often face PA restrictions and are often prescribed beta-blockers for disease management. The aim of this study was to determine if PA levels were lower in patients with LQTS compared with healthy controls. Methods: Participants with LQTS from an inherited arrhythmia clinic completed the Physical Activity Questionnaire for Children and Adolescents (PAQ-C/A) and an exercise stress test. PAQ score (a general measure of PA for youth, unitless) and endurance time were compared with healthy controls. Conclusions: Despite guideline recommendations restricting PA, risk of sudden cardiac death, and use of beta-blockers, our cohort of patients with LQTS reported similar PA levels as healthy controls.
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Chen et al. (2022) conducted a case-control in Long QT syndrome (LQTS). Long QT syndrome (exposure) vs. Healthy controls was evaluated on Physical activity levels (PAQ-C/A score) and endurance time (p=< 0.0001). Paediatric patients with long QT syndrome reported similar physical activity levels as healthy controls despite guideline recommendations restricting physical activity and use of beta-blockers.
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