Key result
Seven high-risk ECG patterns lacking standard criteria represent STEMI equivalents carrying significant risk.
Why the study?
Certain high-risk electrocardiogram presentations in acute coronary syndrome lack diagnostic criteria for STEMI but represent STEMI equivalent syndromes or carry significant risk.
Recognition of specific high-risk ECG patterns in ACS patients without classic STEMI criteria is essential for identifying STEMI equivalents and preventing adverse outcomes.
Supports recognition of these ECG patterns in ACS; leaves open prospective validation before practice change.
This review considers high-risk electrocardiographic patterns in the acute coronary syndrome (ACS) patient; we review 7 electrocardiogram presentations lacking diagnostic criteria for ST-segment elevation myocardial infarction (STEMI) yet likely representing either STEMI equivalent syndromes or ACS presentations with significant short-and long-term risk. The STEMI equivalent presentations include acute posterior wall myocardial infarction, the hyperacute T-wave of early STEMI, de Winter syndrome, first diagonal of the left anterior descending artery occlusion, and left bundle branch block modified Sgarbossa positive findings. High-risk presentation, not felt to be STEMI equivalent entities yet still possessing significant risk of short-and long-term adverse outcome, include lead aVR ST-segment elevation and Wellens syndrome. The features of each presentation, highlighting the electrocardiographic abnormalities, are presented and discussed.
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Brady et al. (2025) conducted a review in Acute coronary syndrome. High-risk electrocardiographic patterns was evaluated. Seven high-risk electrocardiogram presentations lacking diagnostic criteria for STEMI, such as acute posterior wall MI and Wellens syndrome, represent STEMI equivalents or carry significant risk.
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