Resistance to macrolides and tetracyclines is increasing among streptococci and co-occurs as their resistance determinants are carried on the same mobile element. We developed a multiplex PCR to facilitate simultaneous and specific detection of resistance determinants for both macrolides [ erm (A), erm (B), and mef (A/E)] and tetracyclines [ tet (M), tet (O), tet (K), and tet (L)] in streptococci.
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Malhotra‐Kumar et al. (2005) studied this question.
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