Key result
In ICU patients after cardiac arrest, median mean circulatory filling pressure was 15 mmHg (IQR 12-18), and was higher with positive fluid balance, vasopressors/inotropes, and mechanical ventilation.
Cohort (n=311)
In ICU patients after cardiac arrest, the median mean circulatory filling pressure is 15 mmHg, which is higher with positive fluid balance, vasopressor/inotrope use, and mechanical ventilation.
Post-arrest ICU Pmcf measurement should not yet alter fluid or vasopressor decisions; leaves open its role in guiding resuscitation.
In a cohort of 311 intensive care unit (ICU) patients, median mean circulatory filling pressure (Pmcf) measured after cardiac arrest was 15 mmHg (interquartile range 12-18). In 48% of cases, arterial blood pressure remained higher than central venous pressure, but correction for arterial-to-venous compliance differences did not result in clinically relevant alterations of Pmcf. Fluid balance, use of vasopressors or inotropes, and being on mechanical ventilation were associated with a higher Pmcf.
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Wijnberge et al. (2020) conducted a cohort in Cardiac arrest in the intensive care unit (n=311). Measurement of mean circulatory filling pressure (Pmcf) was evaluated on Mean circulatory filling pressure (Pmcf). In ICU patients after cardiac arrest, median mean circulatory filling pressure was 15 mmHg (IQR 12-18), and was higher with positive fluid balance, vasopressors/inotropes, and mechanical ventilation.
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