Why the study?
Does a regimen of aspirin and ticlopidine without heparin reduce bleeding and vascular complications compared to a regimen with heparin in patients with AMI after successful primary coronary stenting?
Population
152 consecutive patients with acute myocardial infarction on Killip score 1 or 2 who underwent primary…
Comparison
Aspirin and ticlopidine without further heparin… vs Aspirin, ticlopidine, and further intravenous…
Design
Cohort
Follow-up
30 days
Authors
Loading...
Hypothesis-generating for heparin omission after primary stenting in AMI; prospective randomized trials needed before practice change.
Does a regimen of aspirin and ticlopidine without heparin reduce bleeding and vascular complications compared to a regimen with heparin in patients with AMI after successful primary coronary stenting?
Omitting routine heparin infusion after successful primary coronary stenting in AMI patients reduces bleeding and vascular complications without increasing the risk of major cardiac events.
Yip et al. (2000) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: