Why the study?
Does coronary thrombosis precede myocardial necrosis in acute myocardial infarction?
Does coronary thrombosis precede myocardial necrosis in acute myocardial infarction?
This review discusses the pathophysiological sequence of coronary thrombosis and myocardial necrosis in fatal ischemic heart disease.
Supports thrombosis preceding necrosis in fatal IHD; leaves open timing and relevance in nonfatal or reperfused AMI.
IN RECENT years the role of coronary thrombosis as a precipitating cause of acute myocardial infarction (AMI) has been questioned. "Which comes first, coronary thrombosis or myocardial necrosis?" Before attempting to answer this ques- tion, changes observed routinely in the coronary arteries in fatal ischemic heart disease (IHD) will be reviewed:
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William C. Roberts (1974) studied this question.
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