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January 1, 2003Stroke

Poststroke Depression

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Authors

ABAnu BergSouth Karelia Central HospitalHPHeikki PalomäkiSocial Insurance InstitutionMLMatti LehtihalmesUniversity of Oulu

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Implication

Randomized trial reveals persistent depressive symptoms in poststroke patients, highlighting a chronic course linked to initial stroke severity and male sex.

Key Points

  • To examine the longitudinal course, associated clinical features, and predictors of depressive symptoms during the first 18 months following a stroke.
  • Followed 100 poststroke patients participating in an antidepressant trial at 2 weeks and 2, 6, 12, and 18 months.
  • Evaluated mood using the Beck Depression Inventory, Hamilton Rating Scale for Depression, and DSM-III-R criteria, with stroke severity measured by the Scandinavian Stroke Scale.
  • Overall, 54% of patients exhibited depressive symptoms during follow-up; 46% of those depressed within the first 2 months remained depressed at 12 or 18 months, while only 12% developed new-onset depression later.
  • Depressive symptoms correlated with older age during the first 2 months, stroke severity from 6 to 12 months, and male sex at 18 months, with no observed link to lesion location.

Cite This Study

Berg et al. (2003) studied this question.

synapsesocial.com/papers/6a1b71dfdb618aee6aabe795https://doi.org/10.1161/01.str.0000048149.84268.07
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Depressed Mood After Stroke1987 · 290 citations
  2. 2Prevention of poststroke depression: 1 year randomised placebo controlled double blind trial of mianserin with 6 month follow up after therapy1999 · 117 citations
  3. 3Poststroke Depression in Acute Phase after Stroke2001 · 96 citations
  4. 4Poststroke Depression Correlates With Cognitive Impairment and Neurological Deficits1999 · 436 citations
  5. 5Depression After Stroke1998 · 374 citations