What does this research mean for the field?

Modified left ventricular reconstruction for post-infarct left ventricular aneurysm results in similar early and late mortality compared to linear repair, but significantly improves left ventricular ejection fraction and reduces major adverse cardiac and cerebrovascular events and hospital readmissions. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

June 10, 2009Interactive Cardiovascular and Thoracic SurgeryOpen Access

Surgery of left ventricular aneurysm: a propensity score-matched study of outcomes following different repair techniques

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Why the study?

Does modified left ventricular reconstruction improve clinical outcomes compared to linear repair in patients with post-infarct left ventricular aneurysm?

Population

514 patients consecutively operated on for post-infarct left ventricular aneurysm, analyzed using a…

Comparison

Modified left ventricular reconstruction (VR) vs Linear repair (LR)

Design

Cohort

Authors

ZZZhe ZhengChinese Academy of Medical Sciences & Peking Union Medical College HFHuishou FanQingdao University WFWei FengQingdao University

Discussion

Member takes

Implication

May support VR over LR to reduce MACCEs/readmissions in post-infarct LVA; hypothesis-generating, needs RCTs before practice change.

Structured PICO

Does modified left ventricular reconstruction improve clinical outcomes compared to linear repair in patients with post-infarct left ventricular aneurysm?

Population

514 patients consecutively operated on for post-infarct left ventricular aneurysm (LVA), analyzed using a propensity score-matched cohort of 202 patients (n=101 per group).

Intervention

Modified left ventricular reconstruction (VR)

Comparator

Linear repair (LR)

Outcome

Early and late outcomes including operative mortality, major adverse cardiac and cerebrovascular events (MACCEs), hospital readmissions, overall long-term mortality, and cardiac mortalityhard clinical

Modified left ventricular reconstruction for post-infarct LVA reduces MACCEs and hospital readmissions compared to linear repair, despite similar mortality rates.

Cite This Study

Zheng et al. (2009) studied this question.

synapsesocial.com/papers/6a1b7d576bdb5bd52d1cea1f https://doi.org/10.1510/icvts.2009.207134

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Surgery of left ventricular aneurysm: a propensity score-matched study of outcomes following different repair techniques

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Surgery of left ventricular aneurysm: a propensity score-matched study of outcomes following different repair techniques

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider