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Left ventricular hypertrophy preserves systolic function but leads to diastolic dysfunction, impaired coronary reserve, and increased ischemia susceptibility, requiring management of pressure overload and tachycardia.
The hypertrophied heart generally preserves systolic function, but it pays a price in diastolic dysfunction. Coronary reserve is impaired and susceptibility to myocardial ischemia increased. The pathophysiology is managed by addressing causes of pressure overload, preventing tachycardia, or, of course, by specific strategies to reduce or eliminate ischemia.
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Beverly H. Lorell (1992) studied this question.
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