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October 16, 2021Journal of Clinical MedicineOpen Access

The Index of Microcirculatory Resistance after Primary Percutaneous Coronary Intervention Predicts Long-Term Clinical Outcomes in Patients with ST-Segment Elevation Myocardial Infarction

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Why the study?

It was unclear whether the index of microcirculatory resistance predicts clinical long-term outcomes in patients with STEMI.

Does a high index of microcirculatory resistance (IMR > 29) predict death or hospitalization for heart failure in STEMI patients after primary PCI?

Population

316 STEMI patients who underwent primary PCI

Comparison

IMR > 29 vs IMR <= 29

Follow-up

Mean 65 months

Authors

GYGwang-Seok YoonSASung Gyun AhnSWSeong‐Ill Woo

Discussion

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Member takes

Overview

High IMR may aid post-PCI risk stratification in STEMI; leaves open whether targeted interventions improve outcomes.

Structured PICO

Does a high index of microcirculatory resistance (IMR > 29) predict death or hospitalization for heart failure in STEMI patients after primary PCI?

P
Population
316 patients with ST-segment Elevation Myocardial Infarction (STEMI) who underwent primary percutaneous coronary intervention (PCI) from 2005 to 2015
I
Intervention
High index of microcirculatory resistance (IMR > 29) measured using pressure sensor/thermistor-tipped guidewire after primary PCI
C
Comparator
Low index of microcirculatory resistance (IMR ≤ 29)
O
Outcome
Composite rate of death or hospitalization for heart failure (HF) over a mean follow-up period of 65 monthscomposite

A high index of microcirculatory resistance (>29) measured immediately after primary PCI is an independent predictor of long-term mortality and heart failure hospitalization in patients with STEMI.

Cite This Study

Yoon et al. (2021) studied this question.

synapsesocial.com/papers/6a1b84e76bdb5bd52d1ceafchttps://doi.org/10.3390/jcm10204752
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