Crosstalk between Oxidative and Nitrosative Stress and Arterial Stiffness

Ioana Mozoş; Constantin Luca

doi:10.2174/1570161115666170201115428

February 23, 2017Current Vascular Pharmacology

Crosstalk between Oxidative and Nitrosative Stress and Arterial Stiffness

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Key Points

The aim is to explore the interplay between oxidative and nitrosative stress and its impact on arterial stiffness.
Investigated the relationship between oxidative stress and arterial stiffness.
Analyzed levels of reactive oxygen species and reactive nitrogen species.
Evaluated the potential implications for cardiovascular disorders.
Demonstrated that increased oxidative stress correlates with greater arterial stiffness.
Found elevated levels of reactive nitrogen species associated with reduced arterial elasticity.

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Implication

Supports oxidative-nitrosative crosstalk in arterial stiffness; leaves open whether targeting these pathways improves outcomes.

Abstract

Background: Arterial stiffness, the expression of reduced arterial elasticity, is an effective predictor of cardiovascular disorders. Oxidative stress is an imbalance between exposure to toxic reactive oxygen species (ROS) and antioxidant systems. The increase in reactive nitrogen species (RNS) is termed nitrosative stress.

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Cite This Study

Mozoş et al. (2017) studied this question.

synapsesocial.com/papers/6a1b93e7376b1af6e80c7b07 https://doi.org/10.2174/1570161115666170201115428

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Crosstalk between Oxidative and Nitrosative Stress and Arterial Stiffness

Key Points

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Implication

Abstract

Discussion

Cite This Study

Crosstalk between Oxidative and Nitrosative Stress and Arterial Stiffness

Key Points

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Implication

Abstract

Discussion

Cite This Study

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