Why the study?
Does daily aspirin therapy improve lifetime quality-adjusted life years in US adults aged 30 to 85 without prior myocardial infarction?
Does daily aspirin therapy improve lifetime quality-adjusted life years in US adults aged 30 to 85 without prior myocardial infarction?
The net benefit of daily aspirin for primary prevention is highly dependent on baseline cardiovascular risk and the patient's personal disutility of taking daily medication.
Authors
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Disutility-adjusted thresholds limit aspirin primary prevention benefit to higher-risk patients; leaves optimal strategies open pending prospective trials.
Sussman et al. (2011) studied this question.
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