Why the study?
What is the prevalence and clinical significance of atrial fibrillation in adults with large atrial septal defects?
What is the prevalence and clinical significance of atrial fibrillation in adults with large atrial septal defects?
Atrial fibrillation is present in nearly one-fifth of adults with large atrial septal defects and serves as an indicator of left atrial enlargement, elevated left atrial pressure, and potential left ventricular failure.
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Supports AF monitoring in older adults with large ASDs; extends prior impressions but remains hypothesis-generating.
Gerasim Tikoff (1968) studied this question.
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