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August 1, 1965Archives of Neurology

Human Cerebrovascular Response Time to Elevation of Arterial Carbon Dioxide Tension

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Authors

WSW ShapiroBahçeşehir UniversityAWA. J. WassermanUnited States Department of Veterans AffairsJPJohn L. PattersonGeisinger Medical Center

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Implication

Cerebrovascular response time to carbon dioxide tension elevation is explored, indicating gaps in understanding.

Key Points

  • This research aims to clarify the time required for the full cerebral vasodilator response to increased carbon dioxide in the blood.
  • Utilized a thermoelectric device to measure blood flow changes continuously in the jugular bulb.
  • Reviewed historical methodologies such as the nitrous oxide method for quantifying cerebral blood flow.
  • Results from past studies indicate cerebral vasodilation occurs with carbon dioxide inhalation, though timing remains inadequately defined.
  • Previous techniques lacked in vivo calibration and faced technical constraints affecting reliability.

Cite This Study

Shapiro et al. (1965) studied this question.

synapsesocial.com/papers/6a1bc1bb01af05bf0da8e98ehttps://doi.org/10.1001/archneur.1965.00470020020003
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