Why the study?
Does long-term treatment with ramipril and vitamin E reduce atherosclerosis progression in high-risk patients ≥55 years of age with vascular disease or diabetes?
Does long-term treatment with ramipril and vitamin E reduce atherosclerosis progression in high-risk patients ≥55 years of age with vascular disease or diabetes?
Long-term treatment with ramipril, but not vitamin E, significantly reduced the progression of atherosclerosis as measured by carotid intimal medial thickness in high-risk patients.
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Ramipril slows carotid atherosclerosis progression in high-risk patients; confirms ACE inhibitor vascular benefits independent of vitamin E.
Lonn et al. (2001) studied this question.
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