Concealed arrhythmogenic syndromes: the hidden substrate of idiopathic ventricular fibrillation?
Why the study?
Do incompletely penetrant genetic defects underlie idiopathic ventricular fibrillation?
Population
Survivors of cardiac arrest and victims of sudden death with no identifiable structural heart disease
Design
Review
Authors
Discussion
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Member takes
Implication
May support genetic evaluation in unexplained VF; leaves open the contribution of incomplete penetrance to sudden death burden.
Structured PICO
Do incompletely penetrant genetic defects underlie idiopathic ventricular fibrillation?
P
Population
Survivors of cardiac arrest and victims of sudden death with no identifiable structural heart disease (idiopathic ventricular fibrillation)
Incompletely penetrant genetic defects may explain a proportion of sudden cardiac deaths previously classified as idiopathic ventricular fibrillation.
Cite This Study
Silvia G. Priori (2001) studied this question.