What question did this study set out to answer?

To review the emergence of antimicrobial resistance among common middle ear pathogens and evaluate alternative treatment strategies for acute otitis media.

January 1, 1994The Pediatric Infectious Disease Journal

Assessing the treatment alternatives for acute otitis media

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Authors

MPMichael E. PichicheroRochester General Hospital

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Implication

Clinical review reveals widespread antibiotic resistance in middle ear pathogens among pediatric populations, highlighting the urgent need to evaluate alternative therapies for acute otitis media.

Key Points

To review the emergence of antimicrobial resistance among common middle ear pathogens and evaluate alternative treatment strategies for acute otitis media.
Assessed resistance patterns resulting from historical overuse of first-line amoxicillin.
Examined bacterial resistance data for nasopharyngeal isolates among pediatric daycare populations.
Prolonged amoxicillin overuse has driven the emergence of beta-lactamase-producing Haemophilus influenzae and Moraxella catarrhalis.
In community daycare settings, 20% to 30% of Streptococcus pneumoniae isolates are resistant to penicillin and amoxicillin, and 30% are resistant to trimethoprim-sulfamethoxazole.

Cite This Study

Michael E. Pichichero (1994) studied this question.

synapsesocial.com/papers/6a1bcedcc97d63156a5ef829 https://doi.org/10.1097/00006454-199401001-00007

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Implication

Clinical review reveals widespread antibiotic resistance in middle ear pathogens among pediatric populations, highlighting the urgent need to evaluate alternative therapies for acute otitis media.

Assessing the treatment alternatives for acute otitis media

Discussion

Member takes

Implication

Key Points

Cite This Study

Assessing the treatment alternatives for acute otitis media

Discussion

Member takes

Implication

Key Points

Cite This Study

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