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Demonstrates improved identification of α-motoneuron subtypes in mice, indicating enhanced research capability.
• A novel multiplex protocol enables labeling of four major α-MN types(S, FR, FI, FF) • Osteopontin, SK2 and SK3 parses out α-MN sub-types • Refined IF protocols for defining α-MN populations in mouse lumbar spinal cord • SK2 and SK3 labels 99% of α-MNs
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Garrett et al. (2026) studied this question.
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