Key result
Effective arterial elastance relates more closely to pulsatile than resistive indices in inoperable CTEPH.
Why the study?
Does effective arterial elastance relate more closely to pulsatile than resistive indices during routine hemodynamic assessment of inoperable CTEPH?
Observational
Does effective arterial elastance relate more closely to pulsatile than resistive indices during routine hemodynamic assessment of inoperable CTEPH?
Effective arterial elastance (Ea) serves as an integrative descriptor of total pulmonary arterial load, incorporating both steady and pulsatile components of right ventricular afterload in patients with inoperable CTEPH.
Ea may integrate pulmonary load in inoperable CTEPH assessment; leaves open outcome validation.
Extract Increased pulmonary arterial (PA) load is a central determinant of outcome in pulmonary hypertension (PH) because of its impact on right ventricular (RV) function and RV–PA coupling [1–3]. In clinical studies, effective arterial elastance (Ea), estimated as systolic pulmonary arterial pressure (sPAP) divided by stroke volume (SV), is widely used as an integrative descriptor of total PA load. Ea incorporates steady and pulsatile components of RV afterload, represented by pulmonary vascular resistance (PVR) and total PA stiffness [1–6].
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Chemla et al. (2026) conducted an observational in Inoperable CTEPH. Hemodynamic assessment was evaluated. Effective arterial elastance relates more closely to pulsatile than resistive indices during routine hemodynamic assessment of inoperable CTEPH.
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