What question did this study set out to answer?

This research aims to explore the combined effects of maternal and neonatal vitamin A supplementation on growth and gene expression in Hanwoo calves, focusing on sex differences.

May 31, 2026Journal of Animal Science and TechnologyOpen Access

Sex-specific effects of maternal and neonatal vitamin A supplementation on blood variables, growth performance, and gene expression in Hanwoo calves

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Authors

XJXue-Cheng JinSoutheast University DPDong-Qiao Peng WJWang-Yong Jeong

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Implication

Randomized trial examines growth and gene expression outcomes in Hanwoo calves with vitamin A supplementation, suggesting implications for development.

Key Points

This research aims to explore the combined effects of maternal and neonatal vitamin A supplementation on growth and gene expression in Hanwoo calves, focusing on sex differences.
Forty-four multiparous Hanwoo cows received varying doses of maternal vitamin A from the third month of gestation until parturition.
Calves were given neonatal vitamin A supplementation in a 2 × 2 factorial design based on sex until day 60.
Assessments included blood variables, growth performance, and gene expression analysis in liver and skeletal muscle.
Maternal vitamin A supplementation significantly increased birth weight in female calves (p < 0.05) and elevated neonatal red blood cell counts and hemoglobin across sexes (p < 0.01).
In female calves, neonatal vitamin A supplementation led to higher serum vitamin A concentrations at weaning (p < 0.05) and increased myogenic factor expression compared to control groups (p < 0.05).
Maternal vitamin A significantly boosted expression of ZNF423 (p < 0.05), while neonatal vitamin A decreased PPARG expression (p < 0.05), with no significant effects seen in male calves.

Cite This Study

Jin et al. (2026) studied this question.

synapsesocial.com/papers/6a1bd0155783ba022b6fbec9 https://doi.org/10.5187/jast.2600132

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Implication

Randomized trial examines growth and gene expression outcomes in Hanwoo calves with vitamin A supplementation, suggesting implications for development.

Sex-specific effects of maternal and neonatal vitamin A supplementation on blood variables, growth performance, and gene expression in Hanwoo calves

Discussion

Member takes

Implication

Key Points

Cite This Study

Sex-specific effects of maternal and neonatal vitamin A supplementation on blood variables, growth performance, and gene expression in Hanwoo calves

Discussion

Member takes

Implication

Key Points

Cite This Study

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