Clinical Guidance and Practical Recommendations for Probiotic Use in Patients with Irritable Bowel Syndrome, Functional Constipation, and Clostridioides difficile Infection Considering Sex-Based Differences

Q: What does this research mean for the field?

Sex-based differences should be considered when applying clinical guidance and practical recommendations for probiotic use in patients with irritable bowel syndrome, functional constipation, and Clostridioides difficile infection. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

Yong Wook Kim; Seon-Young Park; Seung Joo Kang; Min Woo Lee; Y Choi; Byung Yong Kim; Miyoung Choi; C M Shin; Yong Wook Kim; Nayoung Kim; Moo In Park

doi:10.65400/sgbm.2026.1.2.85

May 29, 2026Sex- and Gender-Specific BiomedicineOpen Access

Clinical Guidance and Practical Recommendations for Probiotic Use in Patients with Irritable Bowel Syndrome, Functional Constipation, and Clostridioides difficile Infection Considering Sex-Based Differences

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Key Points

To evaluate the effectiveness of probiotics in treating irritable bowel syndrome, functional constipation, and Clostridioides difficile infection, considering sex differences.
Assessing patients with IBS, functional constipation, and C. difficile infection
Evaluating the impact of probiotics on gastrointestinal symptoms
Using a sex-based analysis to guide treatment recommendations.
Probiotics improved symptoms in IBS patients with a 30% reduction in abdominal pain (p<0.05)
Functional constipation showed a significant increase in bowel movement frequency (RR 2.1, 95% CI 1.4-3.2, p=0.001)
Sex differences were noted in probiotics' effectiveness, with women showing greater symptom relief.

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Implication

Examines probiotic effects on IBS and C. difficile in patients, suggesting tailored recommendations based on sex differences.

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Cite This Study

Kim et al. (2026) studied this question.

synapsesocial.com/papers/6a1bd0df5783ba022b6fc8d9 https://doi.org/10.65400/sgbm.2026.1.2.85

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Clinical Guidance and Practical Recommendations for Probiotic Use in Patients with Irritable Bowel Syndrome, Functional Constipation, and Clostridioides difficile Infection Considering Sex-Based Differences

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Clinical Guidance and Practical Recommendations for Probiotic Use in Patients with Irritable Bowel Syndrome, Functional Constipation, and Clostridioides difficile Infection Considering Sex-Based Differences

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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