The method of administering medication to any part of the body via the skin, vagina, eyes, or throat is known as topical drug delivery. Medication may be used for systemic or local effects. It is possible to create topical formulations with different physicochemical characteristics, such as liquid, semisolid, or solid. A drug emulsion is created and combined with an emulgel to create the topical system. Combining a surfactant and a co-surfactant results in Emulgel, a thermodynamically stable formulation with low interfacial tension and several advantages, including improved permeability and strong thermodynamic stability. When a gelling agent was applied, these emulsions-either water-in-oil or oil-in-water-gelled. incorporating an emulsion into a product. It also increases the gel's stability by acting as a dual-control release mechanism. Combining the terms "emulsion" with "gel" yields "emulgels." Emulgel features a continuous release pattern with dual control. Emulgel increases patient compliance and bioavailability. The pH, viscosity, particle size, zeta potential, stability analysis, skin irritation test, and medication content of the final formulation are all evaluated.
Kokate et al. (Fri,) studied this question.