Key result
Bibliometric analysis of 983 publications identifies China leading cardiac fibrosis research productivity and Australia driving citations.
Why the study?
Given the high global prevalence of cardiac fibrosis leading to heart failure, research trends and regional perspectives in Asia and Oceania needed elucidation.
This bibliometric analysis highlights the growing research output on cardiac fibrosis in Asia and Oceania, identifying key regional contributors and core molecular themes.
Regional bibliometric trends in cardiac fibrosis warrant no practice change; leaves open questions on research priorities and equity.
Background: Cardiac fibrosis is a pathophysiologic condition in heart diseases. It refers to an excess deposition of extracellular matrix, which will cause hardening and stiffness in heart tissues, leading to heart failure. By considering the high prevalence of cardiac fibrosis globally, a bibliometric analysis is conducted to elucidate the research trend involving the unique perspectives in both the Asia and Oceania regions. Methods: Data were retrieved from the Scopus database without restrictions on publication year. Documents related to cardiac fibrosis affiliated with countries in Asia and Oceania were identified using the United Nations geoscheme classifications. The dataset was curated using biblioMagika and OpenRefine. Then, bibliometric mapping was conducted using VOSviewer to analyze co-authorship and keyword co-occurrence networks. Results: A total of 983 publications were identified from 1985 to 2025, with a marked increase in research output from 2010 onwards. China emerged as the leading contributor in terms of productivity and total citations, while Australia showed the highest citation impact per publication. High-impact institutions and authors were identified, and core themes included molecular mechanisms such as transforming growth factor beta signaling, extracellular matrix remodeling, and noncoding RNAs. Conclusion: This study is the first to systematically examine cardiac fibrosis research output across Asia and Oceania using bibliometric methods. It contributes novel insights into the regional dynamics, intellectual structure, and emerging priorities within the field. By identifying key actors, collaboration networks, and knowledge gaps, this research provides valuable guidance for scholars, funding agencies, and policymakers to advance cardiac fibrosis research in regional and global contexts. However, reliance on citation-based metrics may introduce temporal bias, as older publications tend to accumulate more citations over time. Future studies should employ multi-database strategies, altmetric indicators, and machine learning approaches to address these limitations and capture a broader spectrum of research impact.
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Damahuri et al. (2026) studied Cardiac fibrosis. A bibliometric analysis of 983 publications on cardiac fibrosis in Asia and Oceania identified China as the leading contributor in productivity and Australia with the highest citation impact.
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