What does this research mean for the field?

Decreased left atrial appendage emptying flow velocity (LAAEV) measured by transesophageal echocardiography is an independent predictor of increased risk for atrial fibrillation recurrence, stroke, and mortality following successful electrical cardioversion. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

July 30, 2015American Heart JournalOpen Access

Real-time physiologic biomarker for prediction of atrial fibrillation recurrence, stroke, and mortality after electrical cardioversion: A prospective observational study

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Why the study?

Does decreased left atrial appendage emptying flow velocity (LAAEV) predict atrial fibrillation recurrence, stroke, and mortality in patients undergoing successful electrical cardioversion?

Structured PICO

Does decreased left atrial appendage emptying flow velocity (LAAEV) predict atrial fibrillation recurrence, stroke, and mortality in patients undergoing successful electrical cardioversion?

Population

3,251 consecutive patients with sustained atrial fibrillation (AF) undergoing first-time successful transesophageal echocardiography (TEE)-guided electrical cardioversion, mean age 69, 67% men.

Intervention

Lower quartiles of left atrial appendage emptying flow velocity (LAAEV) measured by TEE (first quartile: ≤20.2 cm/s, second quartile: 20.3-33.9 cm/s)

Comparator

Higher quartiles of left atrial appendage emptying flow velocity (LAAEV) (third quartile: 34-49.9 cm/s, fourth quartile: ≥50 cm/s)

Outcome

Atrial fibrillation recurrence, ischemic stroke, and all-cause mortality at 5 yearshard clinical

Decreased left atrial appendage emptying flow velocity measured by TEE is an independent predictor of AF recurrence, ischemic stroke, and mortality following successful electrical cardioversion.

Discussion

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Implication

May refine post-cardioversion risk stratification; hypothesis-generating and should not yet change practice.

Cite This Study

Melduni et al. (2015) studied this question.

synapsesocial.com/papers/6a1bd1e400ee29383e9cf873 https://doi.org/10.1016/j.ahj.2015.07.027

Topics

Left atrial appendage closure Atrial fibrillation Persistent AF management Anticoagulation in AF AF ablation outcomes

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Real-time physiologic biomarker for prediction of atrial fibrillation recurrence, stroke, and mortality after electrical cardioversion: A prospective observational study

Structured PICO

Discussion

Implication

Cite This Study

Topics

Real-time physiologic biomarker for prediction of atrial fibrillation recurrence, stroke, and mortality after electrical cardioversion: A prospective observational study

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider