What question did this study set out to answer?

This study aims to compare cell types and gene expression in skin tissues of two pig breeds at a single-cell level.

May 31, 20260 citationsOpen Access

Multi-omics sequencing of pig skin tissues

Key Points

This study aims to compare cell types and gene expression in skin tissues of two pig breeds at a single-cell level.
Used single-nucleus RNA-sequencing (snRNA-seq) and ATAC-sequencing (snATAC-seq)
Performed bulk RNA-sequencing on skin tissues from Hezuo Tibetan pigs and Bamaxiang pigs
Analyzed data to identify differences in gene expression and regulatory elements.
Identified significantly different expressed genes between Hezuo Tibetan pigs and Bamaxiang pigs
Mapped distinct regulatory elements involved in gene expression variation between the two breeds.

Abstract

We used single-nucleus RNA-sequencing (snRNA-seq) , single-nucleus ATAC-sequencing (snATAC-seq) and Bulk RNA-sequencing from skin tissues of Hezuo Tibetan pigs and Bamaxiang pigs. Using this data, we compared cell types and identified the significantly different expression genes and regulatory elements between two breeds at single cell level.

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王禹(Yu Wang) (Thu,) studied this question.

synapsesocial.com/papers/6a1bd1f65783ba022b6fd71f https://doi.org/https://doi.org/10.26036/cnp0004959

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