What question did this study set out to answer?

May 31, 2026FoodsOpen Access

Protective Effects of Lacticaseibacillus paracasei 63 on DSS-Induced Colitis in Mice

View Full Paper

Ask AI

Bookmark

Authors

Randomized trial evaluates Lacticaseibacillus paracasei 63's protective effects on colitis, suggesting therapeutic potential.

This study aims to evaluate the protective effects of Lacticaseibacillus paracasei 63 on ulcerative colitis.
Used a dextran sulfate sodium (DSS)-induced male ICR mouse model
Assessed effects of oral administration of L. paracasei 63 on various health markers
Measured intestinal inflammation, gut microbiota composition, and systemic inflammation levels.
L. paracasei 63 significantly alleviated colitis symptoms and improved intestinal barrier function
Reduced serum IL-1β and TNF-α levels indicating lower systemic inflammation
Increased SCFA levels, especially acetate, and altered gut microbiota composition.

Wa et al. (2026) studied this question.

View Full Paper

Ask AI

Bookmark