The mortality rate and years of life lost due to cancer in a City of North of Islamic Republic of Iran during the years 2013–2021: joinpoint regression analysis

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Background: By providing a comprehensive analysis of incidence, mortality, and disability, cancer burden studies are tools for cancer control planning. The present study investigates the mortality rate and the years of life lost (YLL) due to cancers in a 9-year period. Methods: All registered cancer deaths in a city of north of Iran during 2013-2021 were considered. Crude, standardized mortality, and YLL of cancers were calculated for different age and sex groups. Also, to check the trend of the YLL, the joinpoint regression has been utilized. Results: During the study years (2013-2021), 3294 cancer deaths occurred. The total YLL because of cancer in the 9 years of the study were 22 228 (9 per 1000 people) in males, 20 824 (8.6 per 1000 people) in females, and 43 052 (8.8 per 1000 people) in both sexes. The average YLL due to malignancy was 11.7 years in males and 15.0 years in females. The highest percentage of YLL in men was caused by cancers of digestive organs and respiratory organs, and in women, cancers of digestive organs and breast. Conclusion: The YLL because of cancer were increasing in both men and women. Addressing the prevention of the underlying causes of YLL - especially gastrointestinal and breast cancers - may significantly affect overall life expectancy.