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January 1, 2000The Journal of Immunology

Suppressor Effector Function of CD4+CD25+ Immunoregulatory T Cells Is Antigen Nonspecific

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Authors

ATAngela M. ThorntonNational Institute of Allergy and Infectious DiseasesESEthan M. ShevachUniversity of North Carolina at Chapel Hill

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Thornton et al. (2000) studied this question.

synapsesocial.com/papers/6a1bdb110a1f7575939d104fhttps://doi.org/10.4049/jimmunol.164.1.183
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation.1996 · 1,325 citations
  2. 2Thymus and Autoimmunity: Production of CD25+CD4+ Naturally Anergic and Suppressive T Cells as a Key Function of the Thymus in Maintaining Immunologic Self-Tolerance1999 · 1,208 citations
  3. 3Peripheral Autoantigen Induces Regulatory T Cells that Prevent Autoimmunity1999 · 276 citations
  4. 4Phenotypically distinct subsets of CD4<sup>+</sup> T cells induce or protect from chronic intestinal inflammation in C. B-17 <i>scid</i> mice1993 · 1,084 citations
  5. 5Anergic T Cells as Suppressor Cells in Vitro1994 · 371 citations