Evaluation of Acute Physiology and Chronic Health Evaluation III predictions of hospital mortality in an independent database

Q: What does this research mean for the field?

The APACHE III model accurately predicts aggregate hospital mortality and demonstrates strong discrimination between survivors and nonsurvivors in U.S. ICU admissions, although calibration across specific risk deciles and certain diagnoses remains imperfect. Novelty: ClaimNovelty.CONFIRMATORY. Consensus alignment: ConsensusAlignment.NEUTRAL.

Jack E. Zimmerman; Douglas P. Wagner; Elizabeth A. Draper; Leslie Wright; Carlos Alzola; William A. Knaus

doi:10.1097/00003246-199808000-00012

August 1, 1998Critical Care Medicine

Evaluation of Acute Physiology and Chronic Health Evaluation III predictions of hospital mortality in an independent database

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Why the study?

Does the APACHE III model accurately predict hospital mortality in an independent sample of U.S. ICU admissions?

Structured PICO

Does the APACHE III model accurately predict hospital mortality in an independent sample of U.S. ICU admissions?

P

Population

37,668 consecutive ICU admissions during 1993 to 1996 across 285 ICUs in 161 U.S. hospitals (including 25,448 admissions at hospitals with >400 beds and 1,074 admissions at hospitals with <200 beds).

I

Intervention

APACHE III hospital mortality prediction model

C

Comparator

Observed hospital mortality

O

Outcome

Accuracy and validity of APACHE III hospital mortality predictions (discrimination and calibration)hard clinical

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Implication

The APACHE III model accurately predicts aggregate hospital mortality in U.S. ICU admissions with excellent discrimination, though calibration across risk deciles remains imperfect.

Discussion

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Cite This Study

Zimmerman et al. (1998) studied this question.

synapsesocial.com/papers/6a1bdbed0a1f7575939d11ae https://doi.org/10.1097/00003246-199808000-00012

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Evaluation of Acute Physiology and Chronic Health Evaluation III predictions of hospital mortality in an independent database

Structured PICO

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Implication

Discussion

Cite This Study

Evaluation of Acute Physiology and Chronic Health Evaluation III predictions of hospital mortality in an independent database

Structured PICO

Ask about this paper

Implication

Discussion

Cite This Study

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